Anti-AQP1 / Aquaporin 1 Antibody (C-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC |
---|---|
Primary Accession | P29972 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 28526 Da |
Dilution | ICC, IHC-P (0.5 - 5 µg/ml), WB (1 - 2 µg/ml) |
Gene ID | 358 |
---|---|
Alias Symbol | AQP1 |
Other Names | AQP1, Aquaporin-1, AQP-1, AQP-CHIP, Aquaporin 1, Aquaporin-CHIP, CHIP28, Colton blood group, Urine water channel, CO |
Target/Specificity | Human, mouse, rat. No cross reactivity with other proteins. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-AQP1 / Aquaporin 1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AQP1 (HGNC:633) |
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Synonyms | CHIP28 |
Function | Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (PubMed:1373524). Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane (PubMed:35835865). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver |
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