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Anti-Adiponectin Antibody (aa19-244, clone 3D11)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q15848
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 3D11
Calculated MW 26414 Da
Dilution IHC-P (10 µg/ml), WB (1:2000)
Additional Information
Gene ID 9370
Alias Symbol ADIPOQ
Other Names ADIPOQ, Adiponectin, ADPN, ACDC, ADIPQTL1, APM-1, APM1, ACRP30, Gelatin-binding protein 28, GBP28, Gelatin-binding protein
Target/Specificity Human Adiponectin
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-Adiponectin Antibody (aa19-244, clone 3D11) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADIPOQ
Function Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Cellular Location Secreted.
Tissue Location Synthesized exclusively by adipocytes and secreted into plasma.
Research Areas
Citations (0)
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Discontinued
Cat# ALS18263
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