|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||48275 Da|
|Dilution||IHC-P (5 µg/ml), WB (1:500 - 1:2000)|
|Other Names||FDPS, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, FPP synthetase, FPS, KIAA1293, FPPS, Geranyltranstransferase, FPP synthase|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-FDPS Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.|
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