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Anti-ARG1 / Arginase 1 Antibody (clone 4E6)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, Flo
Primary Accession P05089
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 4E6
Calculated MW 34735 Da
Dilution Flo (1:100), IHC-P (10 µg/ml), WB (1:1000 - 1:2000)
Additional Information
Gene ID 383
Alias Symbol ARG1
Other Names ARG1, Arginase, liver, Arginase 1, Liver-type arginase, Liver arginase, Arginase-1, Type I arginase
Target/Specificity Human ARG1 / Arginase 1
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-ARG1 / Arginase 1 Antibody (clone 4E6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARG1
Function Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.
Cellular Location Cytoplasm. Cytoplasmic granule. Note=Localized in azurophil granules of neutrophils (PubMed:15546957)
Tissue Location Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409)
Research Areas
Citations (0)
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$ 467.50
Cat# ALS18274
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