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Anti-DBP5 / SON Antibody (aa1413-1628)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18583
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 263830 Da
Dilution ICC (1:100 - 1:1000), IF (1:100 - 1:1000), IHC-P (5 µg/ml)
Additional Information
Gene ID 6651
Alias Symbol SON
Other Names SON, C21orf50, DBP5, DBP-5, KIAA1019, NREBP, Protein SON, Protein DBP-5, SON DNA binding protein, NRE-binding protein, SON3, BASS1
Target/Specificity Human DBP5 / SON.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-DBP5 / SON Antibody (aa1413-1628) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SON
Synonyms C21orf50, DBP5, KIAA1019, NREBP
Function RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence: 5'- GA[GT]AN[CG][AG]CC-3'. May indirectly repress hepatitis B virus (HBV) core promoter activity and transcription of HBV genes and production of HBV virions.
Cellular Location Nucleus speckle. Note=Colocalizes with the pre-mRNA splicing factor SRSF2
Tissue Location Widely expressed, with the higher expression seen in leukocyte and heart
Research Areas
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$ 395.00
Cat# ALS18277
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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