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Anti-TSAP6 / STEAP3 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q658P3
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 54601 Da
Dilution IHC-P (1:100), WB (1:500 - 1:2000)
Additional Information
Gene ID 55240
Alias Symbol STEAP3
Other Names STEAP3, Dudulin-2, Dudlin 2, Dudlin-2, Dudulin 2, Metalloreductase STEAP3, HTSAP6, PHyde, Tumor suppressor pHyde, TSAP6, HpHyde, STMP3
Target/Specificity Human TSAP6 / STEAP3
Reconstitution & Storage Affinity purified
PrecautionsAnti-TSAP6 / STEAP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TSAP6
Function Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Cellular Location Endosome membrane; Multi-pass membrane protein. Note=Localizes to vesicular-like structures at the plasma membrane and around the nucleus
Tissue Location Expressed in adult bone marrow, placenta, liver, skeletal muscle and pancreas. Down-regulated in hepatocellular carcinoma.
Research Areas
Citations (0)

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$ 395.00
Cat# ALS18319
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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