|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||38782 Da|
|Dilution||IHC-P (1:100), WB (1:200 - 1:1000)|
|Other Names||OGG1, 8-oxoguanine DNA glycosylase, AP lyase, HMMH, N-glycosylase/DNA lyase, HOGG1, OGH1, OGG1 type 1f, MMH, MUTM|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-OGG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MMH, MUTM, OGH1|
|Function||DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion.|
|Cellular Location||Nucleus, nucleoplasm. Nucleus speckle. Nucleus matrix. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells Isoform 2A: Mitochondrion.|
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