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Anti-POLK / DNA Polymerase Kappa Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q9UBT6
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 98809 Da
Dilution IF (1:50 - 1:200), IHC-P (1:100), WB (1:500 - 1:2000)
Additional Information
Gene ID 51426
Alias Symbol POLK
Other Names POLK, DINP, DNA polymerase kappa, DINB1, DINB protein
Target/Specificity Human POLK / DNA Polymerase Kappa
Reconstitution & Storage Affinity purified
PrecautionsAnti-POLK / DNA Polymerase Kappa Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POLK
Synonyms DINB1
Function DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
Cellular Location Nucleus. Note=Detected throughout the nucleus and at replication foci
Tissue Location Detected at low levels in testis, spleen, prostate and ovary. Detected at very low levels in kidney, colon, brain, heart, liver, lung, placenta, pancreas and peripheral blood leukocytes.
Research Areas
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$ 395.00
Cat# ALS18344
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