Anti-LIPC / Hepatic Lipase Antibody (aa301-350)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P11150 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 55914 Da |
Dilution | ELISA, IHC-P (1:50), WB |
Gene ID | 3990 |
---|---|
Alias Symbol | LIPC |
Other Names | LIPC, Hepatic lipase, HL, HDLCQ12, Hepatic triglyceride lipase, Lipase member C, HTGL, Lipase, hepatic, Triacylglycerol lipase hepatic, Hepatic triacylglycerol lipase |
Target/Specificity | LIPC Antibody detects endogenous levels of LIPC. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-LIPC / Hepatic Lipase Antibody (aa301-350) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LIPC |
---|---|
Synonyms | HTGL |
Function | Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles (PubMed:7592706, PubMed:8798474, PubMed:12032167, PubMed:26193433). Also exhibits lysophospholipase activity (By similarity). Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates (By similarity). In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position (PubMed:26193433). |
Cellular Location | Secreted. |
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