|Application ||WB, IHC-P, E|
|Calculated MW||35870 Da|
|Dilution||ELISA, IHC-P (1:50), WB|
|Other Names||PTGR1, PGR1, ZADH3, PRG-1, LTB4DH, Prostaglandin reductase 1|
|Target/Specificity||PTGR1 Antibody detects endogenous levels of total PTGR1 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-PTGR1 / LTB4DH Antibody (aa75-124) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.|
|Tissue Location||High expression in the kidney, liver, and intestine but not in leukocytes.|
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