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Anti-OPA1 Antibody (aa901-950)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60313
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 111631 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 4976
Alias Symbol OPA1
Other Names OPA1, KIAA0567, MGM1, LargeG, NPG, NTG, Optic atrophy protein 1
Target/Specificity OPA1 antibody detects endogenous levels of OPA1.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-OPA1 Antibody (aa901-950) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OPA1
Synonyms KIAA0567
Function Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. May also play a role in mitochondrial genome maintenance.
Cellular Location Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space
Tissue Location Highly expressed in retina. Also expressed in brain, testis, heart and skeletal muscle. Isoform 1 expressed in retina, skeletal muscle, heart, lung, ovary, colon, thyroid gland, leukocytes and fetal brain. Isoform 2 expressed in colon, liver, kidney, thyroid gland and leukocytes. Low levels of all isoforms expressed in a variety of tissues.
Research Areas
Citations (0)

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$ 450.00
Cat# ALS18375
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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