|Application ||WB, IHC-P|
|Calculated MW||15508 Da|
|Dilution||IHC-P (5 µg/ml), WB|
|Other Names||HIST3H3, Histone H3.1t, H3t, Histone 3, H3, Histone cluster 3, H3|
|Reconstitution & Storage||Purified|
|Precautions||Anti-HIST3H3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|
|Cellular Location||Nucleus. Chromosome.|
|Tissue Location||Expressed in testicular cells.|
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