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Anti-SPIB Antibody (aa50-260)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q01892
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 28819 Da
Dilution IHC-P (5 µg/ml), WB
Additional Information
Gene ID 6689
Alias Symbol SPIB
Other Names SPIB, SPI-B, Spi-b transcription factor, Transcription factor Spi-B
Target/Specificity Human SPIB
Reconstitution & Storage Purified
PrecautionsAnti-SPIB Antibody (aa50-260) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.
Cellular Location Isoform 1: Nucleus.
Tissue Location Expressed in plasmacytoid dendritic cells (pDCs) and B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver
Research Areas
Citations (0)

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$ 395.00
Cat# ALS18401
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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