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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-SPIB Antibody (aa50-260)
Anti-SPIB Antibody (aa50-260)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q01892 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 28819 Da |
| Dilution | IHC-P (5 µg/ml), WB |
| Gene ID | 6689 |
|---|---|
| Alias Symbol | SPIB |
| Other Names | SPIB, SPI-B, Spi-b transcription factor, Transcription factor Spi-B |
| Target/Specificity | Human SPIB |
| Reconstitution & Storage | Purified |
| Precautions | Anti-SPIB Antibody (aa50-260) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SPIB |
|---|---|
| Function | Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation. |
| Cellular Location | [Isoform 1]: Nucleus |
| Tissue Location | Expressed in plasmacytoid dendritic cells (pDCs) and B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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If you have any additional inquiries please email technical services at tech@abcepta.com.
$ 467.50
Cat# ALS18401
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