|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||77214 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||FBLN1, Fibulin-1, Fibulin-1, isoform a, FIBL-1, Fibulin 1, FBLN, FIBL1|
|Target/Specificity||Recognizes endogenous levels of Fibulin 1 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-FBLN1 / Fibulin 1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.