|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||47075 Da|
|Dilution||IHC-P (1:50), WB (1:500 - 1:1000)|
|Other Names||IDO2, IDO-2, Indoleamine 2, 3-dioxygenase 2, INDOL1|
|Target/Specificity||Recognizes endogenous levels of IDO2 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-IDO2 / INDOL1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance (PubMed:25691885).|
|Tissue Location||Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174). Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%) (PubMed:25691885).|
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