|Application ||WB, IHC-P, IP|
|Predicted||Human, Mouse, Rat, Bovine|
|Calculated MW||27130 Da|
|Dilution||IHC-P (1:100), IP (1:10 - 1:100), WB (1:500 - 1:1000)|
|Other Names||KCNMB2, BK beta 2, HKCNMB2, Hbeta2, Maxi K beta 2, HCG1646471, K(VCA)beta-2, MaxiK channel beta 2 subunit, SLO-BETA2, BK channel subunit beta-2, BKbeta2, HBETA3, Maxi K channel subunit beta-2, Slo-beta-2|
|Target/Specificity||Recognizes endogenous levels of KCNMB2 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-KCNMB2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues|
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