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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-BATF2 / SARI Antibody (C-Terminus)
Anti-BATF2 / SARI Antibody (C-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q8N1L9 |
| Predicted | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 29398 Da |
| Dilution | IHC-P (1:100), WB (1:500 - 1:1000) |
| Gene ID | 116071 |
|---|---|
| Alias Symbol | BATF2 |
| Other Names | BATF2, B-ATF-2, SARI |
| Target/Specificity | Recognizes endogenous levels of BATF2 protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-BATF2 / SARI Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BATF2 |
|---|---|
| Function | AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). Selectively suppresses CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CCN1 and inhibits CCN1-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CCN1 promoter. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}. |
Research Areas
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