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Anti-RAPH1 Antibody (Internal)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q70E73
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 135256 Da
Dilution IHC-P (1:100), WB (1:500 - 1:1000)
Additional Information
Gene ID 65059
Alias Symbol RAPH1
Other Names RAPH1
Target/Specificity Recognizes endogenous levels of RAPH1 protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-RAPH1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAPH1
Synonyms ALS2CR18, ALS2CR9, KIAA1681, LPD, PREL2,
Function Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion.
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, filopodium. Cytoplasm, cytoskeleton. Note=Recruited to the membrane, via the PH domain, by the phosphoinositide, PI(3,4)P2. Colocalizes with ENAH/VASP at the tips of lamellipodia and filopodia. Also colocalizes with the pathogens, Vaccinia and Enteropathogenic E.coli (EPEC) at the interface between the pathogen and their actin
Tissue Location Isoform RMO1-RAPH1 is ubiquitously expressed with highest levels in brain, heart, ovary and developing embryo. Isoform RMO1 is widely expressed with highest levels in liver. Low expression in B-cells.
Research Areas
Citations (0)
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Discontinued
Cat# ALS18445
Size:

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