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Anti-C1QL3 Antibody (Internal)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q5VWW1
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Dilution IHC-P (1:100), WB (1:500 - 1:1000)
Additional Information
Alias Symbol C1QL3
Other Names C1QL3, C1ql, CTRP13, Complement C1q-like protein 3, C1QTNF13, K100
Target/Specificity Recognizes endogenous levels of C1QL3 protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-C1QL3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C1QL3
Synonyms CTRP13
Function May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production (By similarity).
Cellular Location Secreted.
Tissue Location Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney EMBL; AL353576; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL360230; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC127716; AAI27717.1; -; mRNA EMBL; BC127717; AAI27718.1; -; mRNA CCDS; CCDS31156.1; -. [Q5VWW1-1] RefSeq; NP_001010908.1; NM_001010908.1. [Q5VWW1-1] UniGene; Hs.676792; - UniGene; Hs.745101; - ProteinModelPortal; Q5VWW1; - SMR; Q5VWW1; - iPTMnet; Q5VWW1; - PhosphoSitePlus; Q5VWW1; - BioMuta; C1QL3; - DMDM; 74747449; - PaxDb; Q5VWW1; - PeptideAtlas; Q5VWW1; - PRIDE; Q5VWW1; - ProteomicsDB; 65563; - ProteomicsDB; 65564; -. [Q5VWW1-2] ProteomicsDB; 65565; -. [Q5VWW1-3] TopDownProteomics; Q5VWW1-3; -. [Q5VWW1-3] DNASU; 389941; - Ensembl; ENST00000298943; ENSP00000298943; ENSG00000165985. [Q5VWW1-1] Ensembl; ENST00000619991; ENSP00000480149; ENSG00000165985. [Q5VWW1-3] GeneID; 389941; - KEGG; hsa:389941; - UCSC; uc001ioj.1; human. [Q5VWW1-1] CTD; 389941; - DisGeNET; 389941; - EuPathDB; HostDB:ENSG00000165985.9; - GeneCards; C1QL3; - HGNC; HGNC:19359; C1QL3 MIM; 615227; gene neXtProt; NX_Q5VWW1; - OpenTargets; ENSG00000165985; - PharmGKB; PA134891919; - eggNOG; ENOG410IFA6; Eukaryota eggNOG; ENOG4111FAZ; LUCA GeneTree; ENSGT00760000119052; - HOGENOM; HOG000085653; - HOVERGEN; HBG108220; - InParanoid; Q5VWW1; - OMA; DPYGTKS; - OrthoDB; EOG091G0UOF; - PhylomeDB; Q5VWW1; - TreeFam; TF329591; - GenomeRNAi; 389941; - PRO; PR:Q5VWW1; - Proteomes; UP000005640; Chromosome 10 Bgee; ENSG00000165985; - CleanEx; HS_C1QL3; - GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell GO; GO:0042802; F:identical protein binding; IEA:Ensembl GO; GO:0050807; P:regulation of synapse organization; IEA:Ensembl Gene3D; 2.60.120.40; -; 1 InterPro; IPR001073; C1q_dom InterPro; IPR008160; Collagen InterPro; IPR008983; Tumour_necrosis_fac-like_dom Pfam; PF00386; C1q; 1 Pfam; PF01391; Collagen; 1 PRINTS; PR00007; COMPLEMNTC1Q SMART; SM00110; C1Q; 1 SUPFAM; SSF49842; SSF49842; 1 PROSITE; PS50871; C1Q; 1 2: Evidence at transcript level; Alternative splicing; Collagen; Complete proteome; Reference proteome; Secreted; Signal SIGNAL 1 20 CHAIN 21 255 Complement C1q-like protein 3 /FTId=PRO_0000274337 DOMAIN 61 111 Collagen-like DOMAIN 122 255 C1q. {ECO:0000255|PROSITE- ProRule:PRU00368} COMPBIAS 69 108 Pro-rich VAR_SEQ 63 86 Missing (in isoform 2 and isoform 3) /FTId=VSP_027130 VAR_SEQ 87 104 Missing (in isoform 3) /FTId=VSP_027131 SEQUENCE 255 AA; 26719 MW; AEF2004E14DE07AC CRC64; MVLLLVILIP VLVSSAGTSA HYEMLGTCRM VCDPYGGTKA PSTAATPDRG LMQSLPTFIQ GPKGEAGRPG KAGPRGPPGE PGPPGPMGPP GEKGEPGRQG LPGPPGAPGL NAAGAISAAT YSTVPKIAFY AGLKRQHEGY EVLKFDDVVT NLGNHYDPTT GKFTCSIPGI YFFTYHVLMR GGDGTSMWAD LCKNNQVRAS AIAQDADQNY DYASNSVVLH LEPGDEVYIK LDGGKAHGGN NNKYSTFSGF IIYAD
Research Areas
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$ 425.00
Cat# ALS18449
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