Anti-PLXNA4 / Plexin A4 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q9HCM2 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 212455 Da |
Dilution | IHC-P (1:100), WB (1:500 - 1:1000) |
Gene ID | 91584 |
---|---|
Alias Symbol | PLXNA4 |
Other Names | PLXNA4, KIAA1550, PLXNA4A, Plexin A4, A, Plexin-A4, PLXNA4B, Plexin A4, Plexin A4, B, FAYV2820, PLEXA4, PRO34003 |
Target/Specificity | Recognizes endogenous levels of Plexin A4 protein. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-PLXNA4 / Plexin A4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PLXNA4 |
---|---|
Synonyms | KIAA1550, PLXNA4A, PLXNA4B |
Function | Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
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