|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Bovine|
|Calculated MW||8569 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||APLN, AGTRL1 ligand, Apelin, APEL, Preproapelin, APJ endogenous ligand, XNPEP2|
|Target/Specificity||Recognizes endogenous levels of Apelin protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-Apelin Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.|
|Tissue Location||Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.