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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-KCNIP2 / KCHIP2 Antibody (N-Terminus)
Anti-KCNIP2 / KCHIP2 Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
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Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q9NS61 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 30907 Da |
| Dilution | IHC-P (10 µg/ml), WB (1 - 2 µg/ml) |
| Gene ID | 30819 |
|---|---|
| Alias Symbol | KCNIP2 |
| Other Names | KCNIP2, KCHIP2 |
| Target/Specificity | Human KChIP2 protein. Predicted to react with mouse KChIP2 protein according to sequence homology. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-KCNIP2 / KCHIP2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCNIP2 |
|---|---|
| Synonyms | KCHIP2 |
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity). |
| Cellular Location | [Isoform 1]: Cell membrane {ECO:0000250|UniProtKB:Q9JM59}; Lipid-anchor {ECO:0000250|UniProtKB:Q9JM59}. Note=Detected on lipid rafts (By similarity). {ECO:0000250|UniProtKB:Q9JM59} [Isoform 6]: Cell membrane {ECO:0000250|UniProtKB:Q9JM59}; Lipid-anchor {ECO:0000250|UniProtKB:Q9JM59} |
| Tissue Location | Expressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart |
Research Areas
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Application Protocols
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$ 467.50
Cat# ALS18472
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