|Application ||WB, IHC-P|
|Calculated MW||26959 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||NGF, Beta-nerve growth factor, ProNGF, Beta-NGF, HSAN5, NGFB|
|Target/Specificity||Recognizes endogenous levels of pro-NGF beta protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-NGF Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).|
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