|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Monkey|
|Calculated MW||136044 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||SLC4A7, Bicarbonate transporter, BT, NBC2, NBC3, NBCN1, SBC2, NBC2B, MNBC3, SLC4A6|
|Target/Specificity||Recognizes endogenous levels of SLC4A7 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-SLC4A7 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BT, NBC2, NBC2B, NBC3, NBCn1, SBC2, SLC4|
|Function||Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity.|
|Cellular Location||Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, stereocilium. Note=Also described at the apical cell membrane Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells (By similarity)|
|Tissue Location||Highly expressed in testis and spleen. Also expressed in retina, colon, small intestine, ovary, thymus, prostate, muscle, heart and kidney. Isoform 1 is expressed in skeletal muscle and heart muscle.|
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