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Anti-SRA1 / SRA Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q9HD15 |
| Predicted | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 24400 Da |
| Dilution | IHC-P (1:100), WB (1:500 - 1:1000) |
| Gene ID | 10011 |
|---|---|
| Alias Symbol | SRA1 |
| Other Names | SRA1, SRAP, STRAA1, Pp7684, Steroid receptor coactivator, SRA |
| Target/Specificity | Recognizes endogenous levels of SRA protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-SRA1 / SRA Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SRA1 (HGNC:11281) |
|---|---|
| Function | Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N- terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. |
| Cellular Location | Nucleus. Cytoplasm |
| Tissue Location | Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up-regulated in human tumors of the breast, ovary, and uterus |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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