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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-ANGPTL4 Antibody (Coiled-coil domain, clone Kairos4-397G)   

Anti-ANGPTL4 Antibody (Coiled-coil domain, clone Kairos4-397G)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BY76
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names Kairos4-397G
Calculated MW 45214 Da
Dilution ELISA (1:500 - 1:5000), IHC-P (10 µg/ml), WB (1:500 - 1:5000)
Additional Information
Gene ID 51129
Alias Symbol ANGPTL4
Other Names ANGPTL4, Angiopoietin-like 4, Angiopoietin-related protein 4, Angiopoietin-like protein 4, Fasting-induced adipose factor, NL2, PGAR, Pp1158, ARP4, FIAF, HFARP
Target/Specificity Recognizes the coiled-coil domain (CCD) of human ANGPTL4. Detects a band of ~19kDa by Western blot.
Reconstitution & Storage Protein G purified
PrecautionsAnti-ANGPTL4 Antibody (Coiled-coil domain, clone Kairos4-397G) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ARP4, HFARP, PGAR
Function Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation (By similarity).
Cellular Location Secreted. Secreted, extracellular space, extracellular matrix Note=The unprocessed form interacts with the extracellular matrix This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4 (By similarity).
Tissue Location Expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney.
Research Areas
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$ 395.00
Cat# ALS18494
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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