|Application ||IHC-P, ICC|
|Predicted||Human, Mouse, Rat, Hamster, Monkey|
|Calculated MW||52858 Da|
|Dilution||ICC, IHC-P (5 - 10 µg/ml)|
|Other Names||CNR1, CB-R, CB1 receptor, CB1A, CB1R, Cannabinoid receptor 1, Cannabinoid receptor CB1, Cannabinoid Receptor I, CB1, CB1K5, CANN6, Cannabinoid receptor 1 (brain), CNR, Cannabinoid CB(1) receptor, CB1 cannabinoid receptor, Central cannabinoid receptor|
|Target/Specificity||Human CNR1 / CB1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-CNR1 / CB1 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Widely expressed.|
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