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Anti-STK24 / MST3 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y6E0
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 49308 Da
Dilution ELISA, IHC-P (10 µg/ml), WB
Additional Information
Gene ID 8428
Alias Symbol STK24
Other Names STK24, MST-3, MST3, Serine/threonine kinase 24, STE20-like kinase 3, STE20-like kinase MST3, MST3B, STE20, Sterile 20-like kinase 3
Target/Specificity Human STK24 / MST3
Reconstitution & Storage Caprylic acid and ammonium sulfate precipitation
PrecautionsAnti-STK24 / MST3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STK24
Synonyms MST3, STK3
Function Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress- induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase- independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
Cellular Location Cytoplasm. Nucleus. Membrane. Note=The truncated form (MST3/N) translocates to the nucleus. Colocalizes with STK38L in the membrane
Tissue Location Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex
Research Areas
Citations (0)

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$ 395.00
Cat# ALS18513
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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