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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-BLOC1S1 Antibody
Anti-BLOC1S1 Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P78537 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 17263 Da |
| Dilution | ELISA, IHC-P (7.5 µg/ml), WB |
| Gene ID | 2647 |
|---|---|
| Alias Symbol | BLOC1S1 |
| Other Names | BLOC1S1, BLOS1, BLOC-1 subunit 1, BLOC subunit 1, GCN5-like protein 1, GCN5L1, MICoA, MTA1-interacting coactivator, Protein RT14, RT14 |
| Target/Specificity | Human BLOC1S1 |
| Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
| Precautions | Anti-BLOC1S1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BLOC1S1 |
|---|---|
| Synonyms | BLOS1, GCN5L1, RT14 |
| Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (PubMed:17182842). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). |
| Cellular Location | Mitochondrion intermembrane space. Mitochondrion matrix. Cytoplasm, cytosol. Lysosome membrane |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS18520
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