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Anti-BLOC1S1 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78537
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 17263 Da
Dilution ELISA, IHC-P (7.5 µg/ml), WB
Additional Information
Gene ID 2647
Alias Symbol BLOC1S1
Other Names BLOC1S1, BLOS1, BLOC-1 subunit 1, BLOC subunit 1, GCN5-like protein 1, GCN5L1, MICoA, MTA1-interacting coactivator, Protein RT14, RT14
Target/Specificity Human BLOC1S1
Reconstitution & Storage Caprylic acid and ammonium sulfate precipitation
PrecautionsAnti-BLOC1S1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BLOC1S1
Synonyms BLOS1, GCN5L1, RT14
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 and NDUFA9.
Cellular Location Mitochondrion intermembrane space. Mitochondrion matrix. Cytoplasm, cytosol
Research Areas
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$ 395.00
Cat# ALS18520
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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