|Application ||WB, IHC-P, E|
|Calculated MW||22745 Da|
|Dilution||ELISA, IHC-P (7.5 µg/ml), WB|
|Other Names||CRADD, Death adaptor molecule RAIDD, RAIDD, MRT34|
|Target/Specificity||Human CRADD / RAIDD|
|Reconstitution & Storage||Caprylic acid and ammonium sulfate precipitation|
|Precautions||Anti-CRADD / RAIDD Antibody (aa1-199) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney|
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