|Application ||IHC-P, E|
|Calculated MW||35227 Da|
|Dilution||ELISA, IHC-P (7.5 µg/ml)|
|Other Names||DHRS9, 3-alpha-HSD, 3ALPHA-HSD, RDH-E2, RDHL, RDH15, Retinol dehydrogenase homolog, RDH-TBE, RETSDR8, SDR9C4|
|Reconstitution & Storage||Caprylic acid and ammonium sulfate precipitation|
|Precautions||Anti-DHRS9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||3-alpha-hydroxysteroid dehydrogenase that converts 3- alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. May play a role in the biosynthesis of retinoic acid from retinaldehyde, but seems to have low activity with retinoids. Can utilize both NADH and NADPH.|
|Cellular Location||Microsome membrane. Endoplasmic reticulum membrane. Note=Associated with microsomal membranes|
|Tissue Location||Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node.|
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