|Application ||WB, IHC-P, E|
|Calculated MW||15945 Da|
|Dilution||ELISA, IHC-P (7.5 µg/ml), WB|
|Other Names||COTL1, CLP, Coactosin-like protein|
|Target/Specificity||Human CLP / COTL1|
|Reconstitution & Storage||Caprylic acid and ammonium sulfate precipitation|
|Precautions||Anti-CLP / COTL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.|
|Cellular Location||Cytoplasm, cytoskeleton. Nucleus membrane; Peripheral membrane protein|
|Tissue Location||Widely expressed with highest levels in placenta, lung, kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas|
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