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Anti-CNDP2 Antibody (aa2-475)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q96KP4
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 52878 Da
Dilution ELISA, IHC-P (7.5 µg/ml)
Additional Information
Gene ID 55748
Alias Symbol CNDP2
Other Names CNDP2, CN2, CPGL, CNDP dipeptidase 2, HsT2298, PEPA, Peptidase A
Target/Specificity Human CNDP2
Reconstitution & Storage Caprylic acid and ammonium sulfate precipitation
PrecautionsAnti-CNDP2 Antibody (aa2-475) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNDP2 {ECO:0000303|PubMed:25964343, ECO:0000312|HGNC:HGNC:24437}
Function Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides (By similarity). Mediates threonyl dipeptide catabolism in a tissue- specific way (By similarity). Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism (PubMed:19346245, PubMed:12473676). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). Plays a role in the regulation of cell cycle arrest and apoptosis (PubMed:17121880, PubMed:24395568).
Cellular Location Cytoplasm
Tissue Location [Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568).
Research Areas
Citations (0)
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Discontinued
Cat# ALS18560
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