Anti-CNDP2 Antibody (aa2-475)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | Q96KP4 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 52878 Da |
Dilution | ELISA, IHC-P (7.5 µg/ml) |
Gene ID | 55748 |
---|---|
Alias Symbol | CNDP2 |
Other Names | CNDP2, CN2, CPGL, CNDP dipeptidase 2, HsT2298, PEPA, Peptidase A |
Target/Specificity | Human CNDP2 |
Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
Precautions | Anti-CNDP2 Antibody (aa2-475) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CNDP2 {ECO:0000303|PubMed:25964343, ECO:0000312|HGNC:HGNC:24437} |
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Function | Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides (By similarity). Mediates threonyl dipeptide catabolism in a tissue- specific way (By similarity). Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism (PubMed:19346245, PubMed:12473676). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). Plays a role in the regulation of cell cycle arrest and apoptosis (PubMed:17121880, PubMed:24395568). |
Cellular Location | Cytoplasm |
Tissue Location | [Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568). |
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