|Application ||WB, IHC-P, IF|
|Predicted||Human, Mouse, Rat|
|Calculated MW||50141 Da|
|Dilution||IF, IHC-P (1:100), WB|
|Other Names||EEF1A1, Cervical cancer suppressor 3, CCS-3, CCS3, EEF-1, Elongation factor Tu, EEF1A, EF-Tu, EF1A, Elongation factor 1-alpha 1, GRAF-1EF, LENG7, PTI1, CTCL tumor antigen, EE1A1, EEF1A-1, EF-1-alpha-1, EF1a-like protein, HNGC:16303|
|Target/Specificity||Human EEF1A1 / EEF1A|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-EEF1A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||EEF1A, EF1A, LENG7|
|Function||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.|
|Cellular Location||Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens|
|Tissue Location||Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle|
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