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Anti-TPM1 / Tropomyosin Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09493
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 32709 Da
Dilution IF, IHC-P (1:100), WB
Additional Information
Gene ID 7168
Alias Symbol TPM1
Other Names TPM1, Alpha-tropomyosin, C15orf13, Cardiomyopathy, hypertrophic 3, CMD1Y, CMH3, HTM-alpha, Sarcomeric tropomyosin kappa, TMSA, Tropomyosin, Tropomyosin 1 (alpha), Tropomyosin alpha-1 chain, Tropomyosin-1
Target/Specificity Human TPM1 / Tropomyosin
Reconstitution & Storage Affinity purified
PrecautionsAnti-TPM1 / Tropomyosin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TPM1
Synonyms C15orf13, TMSA
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Cellular Location Cytoplasm, cytoskeleton.
Tissue Location Detected in primary breast cancer tissues but undetectable in normal breast tissues in Sudanese patients Isoform 1 is expressed in adult and fetal skeletal muscle and cardiac tissues, with higher expression levels in the cardiac tissues. Isoform 10 is expressed in adult and fetal cardiac tissues, but not in skeletal muscle. {ECO:0000269|PubMed:15249230, ECO:0000269|Ref.15}
Research Areas
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$ 395.00
Cat# ALS18577
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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