|Application ||WB, IHC-P, IF|
|Predicted||Human, Mouse, Rat|
|Calculated MW||42616 Da|
|Dilution||IF, IHC-P (1:100), WB|
|Other Names||ADIPOR1, Adiponectin receptor 1, Adiponectin Receptor, Adiponectin receptor protein 1, CGI-45, CGI45, ACDCR1, TESBP1A, PAQR1|
|Target/Specificity||Human ADIPOR1/Adiponectin Receptor 1|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-ADIPOR1/Adiponectin Receptor 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.|
|Cellular Location||Membrane; Multi-pass membrane protein Note=Localized to the cell membrane and intracellular organelles|
|Tissue Location||Widely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes Weakly expressed in colon, thymus and small intestine|
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