|Application ||WB, IHC-P, IF|
|Predicted||Human, Mouse, Rat|
|Calculated MW||44225 Da|
|Dilution||IF, IHC-P (1:100), WB|
|Other Names||DRD3, D3 dopamine receptor, D3DR, Dopamine 3 receptor, Dopamine receptor D3, D3nf, Essential tremor 1, ETM1, FET1, D(3) dopamine receptor, Dopamine D3 receptor|
|Target/Specificity||Human DRD3 / Dopamine Receptor D3|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-DRD3 / Dopamine Receptor D3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.|
|Cellular Location||Cell membrane; Multi-pass membrane protein Note=Both membrane-bound and scattered in the cytoplasm during basal conditions. Receptor stimulation results in the rapid internalization and sequestration of the receptors at the perinuclear area (5 and 15 minutes), followed by the dispersal of the receptors to the membrane (30 minutes). DRD3 and GRK4 co- localize in lipid rafts of renal proximal tubule cells|
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