Anti-NTRK3 / TRKC Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q16288 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 94428 Da |
Dilution | IHC-P (1:100), WB |
Gene ID | 4916 |
---|---|
Alias Symbol | NTRK3 |
Other Names | NTRK3, ETV6-NTRK3 fusion, gp145-TrkC, Neurotrophin 3 receptor, TRKC, TrkC tyrosine kinase, NT-3 growth factor receptor, NT3 growth factor receptor, Tyrosine kinase receptor C, Pan Trk, gp145(trkC), Trk-C |
Target/Specificity | Human NTRK3 / TRKC |
Reconstitution & Storage | Affinity purified |
Precautions | Anti-NTRK3 / TRKC Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NTRK3 |
---|---|
Synonyms | TRKC |
Function | Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain |
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