|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||57071 Da|
|Dilution||IHC-P (1:100), WB|
|Other Names||SERPIND1, D22S673, HCII, Heparin cofactor II, HLS2, HC-II, HC2, Leuserpin 2, LS2, HCF2, Heparin cofactor 2, THPH10, Protease inhibitor leuserpin-2, Serpin D1|
|Target/Specificity||Human SERPIND1 / Heparin Cofactor 2|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-SERPIND1 / Heparin Cofactor 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.|
|Tissue Location||Expressed predominantly in liver. Also present in plasma|
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