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Anti-NRP1 / Neuropilin 1 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14786
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 103134 Da
Dilution IHC-P (1:100), WB
Additional Information
Gene ID 8829
Alias Symbol NRP1
Other Names NRP1, BDCA4, CD304, CD304 antigen, VEGF165 receptor, VEGF165R, Neuropilin 1, Neuropilin-1, Np-1, Npn-1, NRP, NP1, Transmembrane receptor
Target/Specificity Human NRP1 / Neuropilin 1
Reconstitution & Storage Affinity purified
PrecautionsAnti-NRP1 / Neuropilin 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRP1
Synonyms NRP, VEGF165R
Function The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location The expression of isoforms 1 and 2 does not seem to overlap. Isoform 1 is expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system. In adult tissues, it is highly expressed in heart and placenta; moderately in lung, liver, skeletal muscle, kidney and pancreas; and low in adult brain Isoform 2 is found in liver hepatocytes, kidney distal and proximal tubules
Research Areas
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$ 395.00
Cat# ALS18614
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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