|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||45467 Da|
|Dilution||IHC-P (1:100), WB|
|Other Names||NEU1, Acetylneuraminyl hydrolase, G9 gene encoding sialidase, G9 sialidase, Exo-alpha-sialidase, Neu, Sialidase-1, Lysosomal sialidase, SIAL1, N-acetyl-alpha-neuraminidase 1, NANH|
|Target/Specificity||Human NEU1 / NEU|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-NEU1 / NEU Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage.|
|Cellular Location||Lysosome membrane; Peripheral membrane protein; Lumenal side. Lysosome lumen. Cell membrane. Cytoplasmic vesicle. Note=Localized not only on the inner side of the lysosomal membrane and in the lysosomal lumen, but also on the plasma membrane and in intracellular vesicles|
|Tissue Location||Highly expressed in pancreas, followed by skeletal muscle, kidney, placenta, heart, lung and liver. Weakly expressed in brain.|
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