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Anti-ANTXR1 / TEM8 Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q9H6X2
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 62789 Da
Dilution IF, IHC-P (1:100), WB
Additional Information
Gene ID 84168
Alias Symbol ANTXR1
Other Names ANTXR1, Tumor endothelial marker 8, Anthrax toxin receptor 1, TEM8
Target/Specificity Human ANTXR1 / TEM8
Reconstitution & Storage Affinity purified
PrecautionsAnti-ANTXR1 / TEM8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANTXR1 {ECO:0000303|PubMed:22912819, ECO:0000312|HGNC:HGNC:21014}
Function Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
Cellular Location Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single- pass type I membrane protein. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia (PubMed:16762926). Colocalizes with actin at the base of lamellipodia (PubMed:16762926).
Tissue Location Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells
Research Areas
Citations (0)
citation

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Discontinued
Cat# ALS18619
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