|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||105373 Da|
|Dilution||IHC-P (1:100), WB|
|Other Names||GRIN1, GluN1, NMDAR1, NR1, MRD8, NMD-R1, NMDA receptor A1, NMDA1, NR1a, GluR zeta 1|
|Target/Specificity||Human GRIN1 / NMDAR1|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-GRIN1 / NMDAR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density Note=Enriched in postsynaptic plasma membrane and postsynaptic densities.|
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