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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-CNGA3 Antibody (aa1-165)   

Anti-CNGA3 Antibody (aa1-165)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q16281
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 78838 Da
Dilution IHC-P (1:100), WB
Additional Information
Gene ID 1261
Alias Symbol CNGA3
Other Names CNGA3, CCNCa, CCNCalpha, CCNC1, CNG channel alpha-3, CNG3, ACHM2, Achromatopsia 2, MCNG3, CNCG3, CNG-3
Target/Specificity Human CNGA3
Reconstitution & Storage Affinity purified
PrecautionsAnti-CNGA3 Antibody (aa1-165) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNGA3
Synonyms CNCG3
Function Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Prominently expressed in retina.
Research Areas
Citations (0)

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$ 395.00
Cat# ALS18626
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