|Application ||WB, E|
|Calculated MW||40403 Da|
|Other Names||PR domain zinc finger protein 12, 211-, PR domain-containing protein 12, PRDM12, PFM9|
|Target/Specificity||This PRDM12 antibody was raised suing purified recombinant GST fusion protein encoding human PRDM12.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PRDM12 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the positive regulation of histone H3-K9 dimethylation.|
|Tissue Location||Not found in adult tissues except in dorsal root ganglia.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
SET domains and histone methylation. Xiao B, et al. Curr Opin Struct Biol, 2003 Dec. PMID 14675547.
A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion. Reid AG, et al. Leukemia, 2004 Jan. PMID 14523459.
The prototypical 4.1R-10-kDa domain and the 4.1g-10-kDa paralog mediate fodrin-actin complex formation. Kontrogianni-Konstantopoulos A, et al. J Biol Chem, 2001 Jun 8. PMID 11274145.
The yin-yang of PR-domain family genes in tumorigenesis. Jiang GL, et al. Histol Histopathol, 2000 Jan. PMID 10668202.
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