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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ACOX1 Antibody   

ACOX1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

  • WB - ACOX1 Antibody AM1847B
    Anti- at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 74 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - ACOX1 Antibody AM1847B
    ACOX1 Monoclonal Antibody (Cat. #AM1847b) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjμgation of the secondary antibody and DAB staining. This data demonstrates the use of the ACOX1 Monoclonal Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - ACOX1 Antibody AM1847B
    Confocal immunofluorescent analysis of ACOX1 Antibody (Cat#AM1847b) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15067
Other Accession NP_009223.2
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 153CT43.1.1
Calculated MW 74424 Da
Additional Information
Gene ID 51
Other Names Peroxisomal acyl-coenzyme A oxidase 1, AOX, Palmitoyl-CoA oxidase, Straight-chain acyl-CoA oxidase, SCOX, ACOX1, ACOX
Target/Specificity This ACOX1 monoclonal antibody is generated from mouse immunized with ACOX1 recombinant protein.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsACOX1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACOX1
Synonyms ACOX
Function Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA.
Cellular Location Peroxisome.
Tissue Location Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart
Research Areas
Citations (0)

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ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.


Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008) Carrozzo, R., et al. Am. J. Med. Genet. A 146A (13), 1676-1681 (2008) Omi, S., et al. J. Biochem. 143(5):649-660(2008)

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$ 295.00
$ 99.00
Cat# AM1847B
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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