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VEGFC antibody ( Ascites)Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AM1886a | 0.1 ml 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
VEGFC antibody ( Ascites) - Product info | |
| Application | WB
|
| Primary Accession | P49767 |
| Reactivity | Human |
| Concentration | Crude ascites |
| Isotype | IgG1,IGK |
| Clone Names | 197CT7.3.4 |
| Calculated MW | 46883 Da |
VEGFC antibody ( Ascites) - Additional info | |
| Gene ID 7424 | |
| Other Names VEGFC; Vascular endothelial growth factor C; Flt4 ligand; Vascular endothelial growth factor-related protein | |
| Target/Specificity This VEGFC monoclonal antibody is generated from mouse immunized with VEGFC recombinant protein. | |
| Dilution WB~~1:1000~8000 | |
| Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions VEGFC antibody ( Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. | |
VEGFC antibody ( Ascites) - Protein Information | |
| Name VEGFC | |
| Function Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors | |
| Cellular Location Secreted. | |
| Tissue Location Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte | |
VEGFC antibody ( Ascites) - Related products
AM1886a: VEGFC antibody ( Ascites)
AP11951a: VEGF3 Antibody (N-term)
AP2042c: VEGFC (VEGF3) Antibody (Center M263)
RI15683: VEGFC predesign siRNA
DC06850: Human VEGFC cDNA Clone
VEGFC antibody ( Ascites) - Application data
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VEGFC (Cat. #AM1886a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the VEGFC antibody detected the VEGFC protein (arrow).
VEGFC antibody ( Ascites) - Research Areas
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BACKGROUND
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq].
REFERENCES
Chen, X., et al. Cancer Sci. 101(11):2384-2390(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Deguchi, K., et al. Anticancer Res. 30(6):2361-2366(2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
