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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CABC1 antibody ( Ascites)   

CABC1 antibody ( Ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - CABC1 antibody ( Ascites) AM1890a
    CABC1 antibody (Cat. #AM1890a) western blot analysis in Widr cell line lysates (35μg/lane).This demonstrates the CABC1 antibody detected the CABC1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NI60
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1,K
Clone Names 216CT7.5.1
Calculated MW 71950 Da
Additional Information
Gene ID 56997
Other Names Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, 2711-, aarF domain-containing protein kinase 3, ADCK3, CABC1
Target/Specificity This CABC1 monoclonal antibody is generated from mouse immunized with CABC1 recombinant protein.
Dilution WB~~1:500~16000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCABC1 antibody ( Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADCK3 (HGNC:16812)
Function Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144). Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway (PubMed:25498144). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144).
Cellular Location Mitochondrion. Membrane; Single-pass membrane protein {ECO:0000255, ECO:0000305|PubMed:25216398}
Tissue Location Widely expressed, with highest levels in adrenal gland, heart, pancreas, nasal mucosa, stomach, uterus and skeletal muscle.
Research Areas
Citations (0)

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This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.


Lagier-Tourenne, C., et al. Am. J. Hum. Genet. 82(3):661-672(2008)
Mollet, J., et al. Am. J. Hum. Genet. 82(3):623-630(2008)
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Iiizumi, M., et al. Cancer Res. 62(5):1246-1250(2002)

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$ 295.00
Cat# AM1890a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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