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NLRP12 antibody (Ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - NLRP12 antibody (Ascites) AM1894a
    NLRP12 antibody (Cat. #AM1894a) western blot analysis in mouse cerebellum tissue lysates (35μg/lane).This demonstrates the NLRP12 antibody detected the NLRP12 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P59046
Other Accession NP_150639.1, NP_653288.1
Reactivity Mouse
Host Mouse
Clonality Monoclonal
Isotype IgM,K
Clone Names 228CT4.1.3
Calculated MW 120173 Da
Additional Information
Gene ID 91662
Other Names NACHT, LRR and PYD domains-containing protein 12, Monarch-1, PYRIN-containing APAF1-like protein 7, Regulated by nitric oxide, NLRP12, NALP12, PYPAF7, RNO
Target/Specificity This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.
Dilution WB~~1:100~1600
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNLRP12 antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NLRP12
Synonyms NALP12, PYPAF7, RNO
Function May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.
Cellular Location Cytoplasm.
Tissue Location Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes.
Research Areas
Citations (0)

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This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.


Bailey, S.D., et al. Diabetes Care (2010) In press :
Cummings, J.R., et al. Tissue Antigens 76(1):48-56(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Fahy, R.J., et al. Am. J. Respir. Crit. Care Med. 177(9):983-988(2008)
Jeru, I., et al. Proc. Natl. Acad. Sci. U.S.A. 105(5):1614-1619(2008)

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$ 295.00
Cat# AM1894a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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