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ELAVL1 AntibodyMouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AM1899b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AM1899b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ELAVL1 Antibody - Product info | |
| Application | WB, IF
|
| Primary Accession | Q15717 |
| Other Accession | NP_001410.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | IgG1,K |
| Clone Names | 224CT6.5.3 |
| Calculated MW | 36092 Da |
ELAVL1 Antibody - Additional info | |
| Gene ID 1994 | |
| Other Names ELAVL1; HUR; ELAV-like protein 1; Hu-antigen R | |
| Target/Specificity This ELAVL1 monoclonal antibody is generated from mouse immunized with ELAVL1 recombinant protein. | |
| Dilution WB~~1:100~1000 IF~~1:10~50 | |
| Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ELAVL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
ELAVL1 Antibody - Protein Information | |
| Name ELAVL1 | |
| Synonyms HUR | |
| Function Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro | |
| Cellular Location Cytoplasm. Nucleus. Note=Translocates into the cytoplasm following phosphorylation by MAPKAPK2 | |
| Tissue Location Ubiquitous. | |
ELAVL1 Antibody - Related products
AM1899a: ELAVL1 antibody (Ascites)
RI11746: ELAVL1 predesign siRNA
ELAVL1 Antibody - Application data
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ELAVL1/MB10217 antibody (Cat. #AM1899b) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ELAVL1/MB10217 antibody detected the ELAVL1/MB10217 protein (arrow).
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Confocal immunofluorescent analysis of ELAVL1 Antibody (Cat#AM1899b) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).
ELAVL1 Antibody - Research Areas
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BACKGROUND
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
REFERENCES
Tholanikunnel, B.G., et al. J. Biol. Chem. 285(44):33816-33825(2010) Drury, G.L., et al. J. Biol. Chem. 285(41):31130-31138(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Raspaglio, G., et al. Cancer Res. 70(14):5891-5900(2010) Ahn, J., et al. Retrovirology 7, 40 (2010) :
